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Detlef Schlöndorff Selected Research

BX 471

4/2005Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.
12/2004CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome.
6/2004Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice.
2/2004Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction.
1/2002A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.

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Detlef Schlöndorff Research Topics

Disease

15Inflammation (Inflammations)
05/2007 - 01/2000
11Glomerulonephritis
12/2006 - 05/2000
10Lupus Nephritis
01/2007 - 07/2001
9Proteinuria
06/2009 - 05/2001
9Fibrosis (Cirrhosis)
04/2005 - 06/2001
6Infections
01/2012 - 01/2003
4Diabetic Nephropathies (Diabetic Nephropathy)
06/2007 - 07/2003
4Kidney Diseases (Kidney Disease)
05/2007 - 05/2000
3Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
03/2014 - 07/2003
3Albuminuria
10/2003 - 05/2001
2HIV Infections (HIV Infection)
08/2009 - 12/2005
2Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
11/2008 - 07/2003
2Ischemia
01/2006 - 02/2003
2Arthritis (Polyarthritis)
12/2005 - 01/2004
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2005 - 03/2004
2Atrophy
04/2005 - 12/2004
2Ureteral Obstruction
02/2004 - 06/2001
2Nephrosclerosis
11/2003 - 07/2003
1Atherosclerosis
08/2009
1Communicable Diseases (Infectious Diseases)
08/2009
1Hypoxia (Hypoxemia)
06/2007
1Microvascular Rarefaction
06/2007
1Hepatitis C
02/2006
1Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
02/2006
1Virus Diseases (Viral Diseases)
01/2006
1Pyelonephritis
12/2005
1Abscess
12/2005
1Lymphadenopathy
12/2005
1Splenomegaly
12/2005
1Hypergammaglobulinemia (Hyperimmunoglobulinemia)
12/2005
1Disease Progression
11/2005
1IGA Glomerulonephritis (IGA Nephropathy)
01/2005
1Sclerosis
12/2004
1Nephrotic Syndrome (Syndrome, Nephrotic)
12/2004
1Arteriosclerosis
09/2004
1Plague (Bubonic Plague)
07/2004
1Pneumococcal Pneumonia
07/2004
1Lung Injury
07/2004
1Renal Insufficiency (Renal Failure)
06/2004
1Experimental Arthritis
01/2004
1Wilms Tumor (Wilm's Tumor)
11/2003

Drug/Important Bio-Agent (IBA)

19ChemokinesIBA
01/2012 - 01/2000
17Chemokine ReceptorsIBA
08/2009 - 05/2000
10Messenger RNA (mRNA)IBA
11/2008 - 01/2002
10Antigen-Antibody Complex (Immune Complex)IBA
02/2006 - 05/2000
8CytokinesIBA
01/2012 - 07/2001
6Chemokine CCL5IBA
02/2006 - 05/2001
5DNA (Deoxyribonucleic Acid)IBA
11/2005 - 02/2003
5BX 471IBA
04/2005 - 01/2002
4Proteins (Proteins, Gene)FDA Link
11/2008 - 07/2001
4Toll-Like Receptors (Toll-Like Receptor)IBA
05/2007 - 03/2004
3Toll-Like Receptor 3IBA
01/2012 - 05/2005
3CollagenIBA
06/2004 - 01/2002
2Double-Stranded RNA (RNA, Double Stranded)IBA
01/2012 - 05/2005
2Nucleic AcidsIBA
12/2006 - 01/2006
2RNA (Ribonucleic Acid)IBA
05/2005 - 03/2004
2CCR ReceptorsIBA
12/2004 - 06/2001
2AntigensIBA
04/2004 - 11/2003
2CC ChemokinesIBA
06/2003 - 06/2001
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2001 - 12/2000
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
03/2014
1Poly I-CIBA
01/2012
1Antiviral Agents (Antivirals)IBA
01/2012
1Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2012
1Viral DNAIBA
01/2012
1Epidermal Growth Factor (EGF)IBA
06/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2007
1Heat-Shock Proteins (Heat-Shock Protein)IBA
05/2007
1BiglycanIBA
05/2007
1NF-kappa B (NF-kB)IBA
11/2006
1Mycophenolic Acid (Cellcept)FDA LinkGeneric
06/2006
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2006
1Viral RNAIBA
02/2006
1salicylhydroxamic acid (SHAM)IBA
01/2006
1Imiquimod (Aldara)FDA LinkGeneric
01/2006
1CD4 Antigens (CD4 Antigen)IBA
12/2005
1Toll-Like Receptor 4IBA
12/2005
1Interferon Type IIBA
05/2005
1Bacterial DNAIBA
05/2005
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2004
1Matrix Metalloproteinases (MMPs)IBA
09/2004
1Metalloproteases (Metalloproteinases)IBA
09/2004
1AngiotensinsIBA
08/2004
1Virulence Factors (Pathogenicity Factors)IBA
07/2004
1Streptococcus pneumoniae plY proteinIBA
07/2004
1AutoantibodiesIBA
06/2004
1Transforming Growth Factor beta (TGF-beta)IBA
06/2004
1OligodeoxyribonucleotidesIBA
03/2004
1Class 3 Receptor-Like Protein Tyrosine PhosphatasesIBA
11/2003
1nephrinIBA
11/2003
1NPHS2 proteinIBA
11/2003
1ActininIBA
11/2003
1Dystroglycans (Dystroglycan)IBA
11/2003
1Amlodipine (Norvasc)FDA LinkGeneric
10/2003
1candesartanIBA
10/2003
1Angiotensin IIIBA
10/2003
1CreatinineIBA
10/2003

Therapy/Procedure

3Therapeutics
04/2007 - 01/2003
2Ligation
12/2006 - 01/2002
1Intravenous Injections
12/2004